The ADAMTS4 Antibody from MyBioSource.com is a Mouse Monoclonal antibody. This antibody recognizes Human antigen. The ADAMTS4 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-:-Ala-393' site